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The application of genomics to identify diagnostic biomarkers, drivers and therapeutic targets for pediatric cancers

The application of genomics to identify diagnostic biomarkers, drivers and therapeutic targets for pediatric cancers

The application of genomics to identify diagnostic biomarkers, drivers and therapeutic targets for pediatric cancers

Veterinary Cancer Society
Veterinary Cancer Society
on behalf of Missouri Veterinary Medical Association

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Normal Price: FREE $12.50

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Launch date: 28 Jan 2016
Expiry Date:

Last updated: 20 Apr 2016

Reference: 161916

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This course is only available to trainees days after purchase. It would need to be repurchased by the trainee if not completed in the allotted time period. This course is no longer available. You will need to repurchase if you wish to take the course again.

Description

The Application of Genomics to Identify Diagnostic Biomarkers, Drivers and Therapeutic Targets for Pedicatric CancersThe presentation will attempt to illustrate the power of genomics in identification of biomarkers, drivers and therapeutic targets for pediatric cancers. I will first to give the background on the success and challenges of treating pediatric cancers. Then I will explain how to use high throughput genomic methods to identify biomarkers, drivers and therapeutic targets for pediatric cancers. The evolving technologies of genomics will be also discussed. I will use FGFR4 as an example to demonstrate how we discovered its expression as a diagnostic marker and then demonstrated it as a target for rhabdomyosarcoma.

Objectives

Learning objectives
• To understand the interaction between biomarkers, drivers, and therapeutic targets
• To understand the application of genomics in the identification of novel biomarkers
• To understand how translation genomics applies to personalized treatment
Veterinary Cancer Society

Author Information Play Video Bio

Veterinary Cancer Society
on behalf of Missouri Veterinary Medical Association

Dr. Jun S. Wei received his Ph.D. degree from Baylor College of Medicine in 1999. At the dawn of the genomic era, he went to learn genomics at the National Human Genome Institute as a postdoctoral fellow while the human genome project was still ongoing. After postdoctoral fellowship, he was recruited to join the NCI in 2001 to study pediatric solid tumors using genomics approaches. He has been using systematic high-throughput approaches including microarrays, next-generation sequencing technologies, and large-scale screenings to improve the understanding of high-risk pediatric cancers. He is the author of over 40 peer-reviewed publications and a holder for 3 patents. He also serves as a reviewer for many scientific journals and funding agencies around world. His works focus on rapid translation from laboratory discovery to the clinic including identification and validation of biomarkers and novel therapeutic targets. He is currently serving as a staff scientist in the Genetics Branch of the NCI’s intramural Center for Cancer Research.

Current Accreditations

This course has been certified by or provided by the following Certified Organization/s:

  • Missouri Veterinary Medical Association
  • 0.25 Hours -
    Exam Attempts: 3
    -
    Exam Pass Rate: 50

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