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Diagnostic Challenges in Mastocytosis: Serum Tryptase, Allele-Specific PCR and GI Pathology

Diagnostic Challenges in Mastocytosis: Serum Tryptase, Allele-Specific PCR and GI Pathology

Diagnostic Challenges in Mastocytosis: Serum Tryptase, Allele-Specific PCR and GI Pathology

Dr. Joseph H. Butterfield (MD FAAAAI), Patrizia Bonadonna (MD CME), Joseph H. Butterfield (MD FAAAAI
Dr. Joseph H. Butterfield (MD FAAAAI), Patrizia Bonadonna (MD CME), Joseph H. Butterfield (MD FAAAAI
on behalf of American Academy of Allergy Asthma & Immunology

$15.00 $ 15.00 $ 15.00

$15.00 $ 15.00 $ 15.00

$ 15.00 $ 15.00 $ 15.00
$ 15.00 $ 15.00 $ 15.00
Normal Price: $15.00 $15.00

Review:

Launch date: 03 Jul 2018
Expiry Date:

Last updated: 22 Aug 2018

Reference: 190524

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Course Availability

This course is only available to trainees days after purchase. It would need to be repurchased by the trainee if not completed in the allotted time period. This course is no longer available. You will need to repurchase if you wish to take the course again.

Description

The problem of evaluating an elevated serum tryptase value is common and widespread. The significance of the elevation depends on several factors that can be sorted out using a comprehensive understanding of the probabilities of mastocytosis, familial tryptasemia and mast cell activation disorder and currently available laboratory tests.

In this session, several paradigms for predicting mastocytosis on the basis of clinical findings and laboratory tests will be discussed. The appropriate subsequent tests and the indications/non-indications for bone marrow biopsy will also be reviewed.

Objectives

Discuss utility and interpretation of elevated tryptase level
Upon completion of this session, participants should be able to discuss utility and interpretation of elevated tryptase level.
Discuss which cases can be evaluated at general allergist level and when a referral to a mastocytosis center is indicated
Upon completion of this session, participants should be able to discuss which cases can be evaluated at general allergist level and when a referral to a mastocytosis center is indicated.
Discuss utility and interpretation of allele-specific PCR and indications for bone marrow biopsy
Upon completion of this session, participants should be able to discuss utility and interpretation of allele-specific PCR and indications for bone marrow biopsy.
Dr. Joseph H. Butterfield (MD FAAAAI), Patrizia Bonadonna (MD CME), Joseph H. Butterfield (MD FAAAAI

Author Information Play Video Bio

Dr. Joseph H. Butterfield (MD FAAAAI), Patrizia Bonadonna (MD CME), Joseph H. Butterfield (MD FAAAAI
on behalf of American Academy of Allergy Asthma & Immunology

Dr. Joseph H. Butterfield, MD FAAAAI, Mayo Clinic, Rochester, MN

Patrizia Bonadonna, MD CME, Azienda Ospedaliera Universitaria Integrata, Verona, Italy

Joseph H. Butterfield, MD FAAAAI, Mayo Clinic, Rochester, MN

Dean D. Metcalfe, MD FAAAAI, NIAID, NIH, Bethesda, MD

Alberto Orfao, MD PhD, Spanish Network on Mastocytosis (REMA), Salamanca, Spain

Current Accreditations

This course has been certified by or provided by the following Certified Organization/s:

  • Accreditation Council for Continuing Medical Education (ACCME)
  • 2.50 Credits
  • California Board of Registered Nursing (CBRN)
  • 2.50 Hours

Faculty and Disclosures

Joseph H. Butterfield, MD FAAAAI

Joseph H. Butterfield, MD FAAAAI

No Conflict
Patrizia Bonadonna, MD CME

Patrizia Bonadonna, MD CME

No Conflict
Dean D. Metcalfe, MD FAAAAI

Dean D. Metcalfe, MD FAAAAI

No Conflict
Alberto Orfao, MD PhD

Alberto Orfao, MD PhD

No Conflict

Additional Contributors

Conflicts Declared

Conflicts of Interest declaration by Author:

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