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Electrochemotherapy Application & Update: Cases from the PNW

Electrochemotherapy Application & Update: Cases from the PNW

Electrochemotherapy Application & Update: Cases from the PNW

Veterinary Cancer Society
Veterinary Cancer Society
on behalf of Missouri Veterinary Medical Association

$ FREE $ FREE $ FREE

$ 25.00 $ 25.00 $ 25.00

$ FREE $ FREE $ FREE
$ 25.00 $ 25.00 $ 25.00
Normal Price: FREE $ 25.00

Review:

Launch date: 15 Apr 2015

Expiry Date:

Last updated: 09 Jun 2017

Reference: 150800

$ FREE $ FREE $ FREE
$ 25.00 $ 25.00 $ 25.00
Electrochemotherapy Application & Update: Cases from the PNW
Exam is embedded in the course
No Exam Available

Latest User Comments

Dr andy abbo DVM, MS, DACVIM (14 Dec 2016)
very good

I would like to...

Course Availability

This course is only available to trainees days after purchase. It would need to be repurchased by the trainee if not completed in the allotted time period. This course is no longer available. You will need to repurchase if you wish to take the course again.

Description

Electrochemotherapy is an anti-cancer treatment that couples local administration of chemotherapy drugs to the delivery of pulses of a specific waveform. The pulses allow for alterations in the cell membrane of the cancer cells such that there is increased uptake of the chemotherapy drugs. Ultimately this leads to the cell dying. It is used in conjunction with chemotherapy (either locally or intravenously), it allows drugs to enter the cells to a very high concentration. these electric pulses can be utilized to cause temporary and reversible permeability of cell membranes to augment the delivery of chemotherapy. The two drugs of choice are Bleomycin and Cisplatin; as they both are relatively large molecules and poorly permeable on their own.

This therapy has received considerable attention in the last 15 years as an emerging way of delivering chemotherapy agents to different tumor types. It can be used as a single modality treatment for small amounts of gross disease or as an adjuvant treatment in humans and our pet species. Preclinical trials and trials in humans have demonstrated excellent anti-tumor effectiveness of electrochemotherapy on various tumor types, minimal toxicity and safety of the procedure.

Veterinary studies have demonstrated that electrochemotherapy is very effective in the treatment of cutaneous and subcutaneous tumors of different histologic subtypes in dogs, cats and horses. We will discuss this technique and go through clinical cases.

Objectives

Objectives
Several novel tumor-targeting and drug-delivery approaches in cancer treatment are currently undergoing intensive investigation, among them physical approaches such as tissue electroporation. Since the early 1980s, electroporation has proved to be effective in facilitating the transport of various molecules across the plasma membrane. By using short, intense electric pulses, the plasma membrane becomes permeable to molecules such as bleomycin and cisplatin that are otherwise deprived of membrane
Veterinary Cancer Society

Author Information Play Video Bio

Veterinary Cancer Society
on behalf of Missouri Veterinary Medical Association

Dr Chelsea Tripp is a Diplomate of the American College of Veterinary Internal Medicine and specializes in Oncology. She received her veterinary degree from the University of Missouri and completed an internship at Animal Cancer Specialists in Seattle. Her three-year residency in medical oncology and a master’s degree looking at the methylation status of lymphoma in dogs was completed at Washington State University.

Dr. Tripp’s areas of interest include client education, oncologic emergencies, clinical pathology, electrochemotherapy, palliative care, and improving the quality of life for end-stage cancer patients. The focus of her approach to the practice of oncology is compassionate care and strengthening the human-animal bond.

Current Accreditations

This course has been certified by or provided by the following Certified Organization/s:

  • Missouri Veterinary Medical Association
  • 1.00 Hours -
    Exam Attempts: 3
    -
    Exam Pass Rate: 50

Faculty and Disclosures

Additional Contributors

Conflicts Declared

Conflicts of Interest declaration by Author:

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User Reviews (1)

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Dr andy abbo DVM, MS, DACVIM (14 Dec 2016)
very good

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